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Early activation of MyD88-mediated autophagy sustains HSV-1 replication in human monocytic THP-1 cells

Autophagy is a cellular degradation pathway that exerts numerous functions in vital biological processes. Among these, it contributes to both innate and adaptive immunity. On the other hand, pathogens have evolved strategies to manipulate autophagy for their own advantage. By monitoring autophagic m...

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Detalles Bibliográficos
Autores principales: Siracusano, Gabriel, Venuti, Assunta, Lombardo, Daniele, Mastino, Antonio, Esclatine, Audrey, Sciortino, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980660/
https://www.ncbi.nlm.nih.gov/pubmed/27509841
http://dx.doi.org/10.1038/srep31302