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Enteric Neural Cells From Hirschsprung Disease Patients Form Ganglia in Autologous Aneuronal Colon

BACKGROUND & AIMS: Hirschsprung disease (HSCR) is caused by failure of cells derived from the neural crest (NC) to colonize the distal bowel in early embryogenesis, resulting in absence of the enteric nervous system (ENS) and failure of intestinal transit postnatally. Treatment is by distal bowe...

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Detalles Bibliográficos
Autores principales: Rollo, Benjamin N., Zhang, Dongcheng, Stamp, Lincon A., Menheniott, Trevelyan R., Stathopoulos, Lefteris, Denham, Mark, Dottori, Mirella, King, Sebastian K., Hutson, John M., Newgreen, Donald F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980742/
https://www.ncbi.nlm.nih.gov/pubmed/28174705
http://dx.doi.org/10.1016/j.jcmgh.2015.09.007