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A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains

Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of skin and soft tissue infections. One of the highly successful and rapidly disseminating clones is MRSA ST22 commonly associated with skin tropism. Here we show that a naturally occurring single amino acid substitution (tyrosine t...

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Detalles Bibliográficos
Autores principales: Mairpady Shambat, Srikanth, Siemens, Nikolai, Monk, Ian R., Mohan, Disha B., Mukundan, Santhosh, Krishnan, Karthickeyan Chella, Prabhakara, Sushma, Snäll, Johanna, Kearns, Angela, Vandenesch, Francois, Svensson, Mattias, Kotb, Malak, Gopal, Balasubramanian, Arakere, Gayathri, Norrby-Teglund, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980769/
https://www.ncbi.nlm.nih.gov/pubmed/27511873
http://dx.doi.org/10.1038/srep31360