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A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of skin and soft tissue infections. One of the highly successful and rapidly disseminating clones is MRSA ST22 commonly associated with skin tropism. Here we show that a naturally occurring single amino acid substitution (tyrosine t...
Autores principales: | Mairpady Shambat, Srikanth, Siemens, Nikolai, Monk, Ian R., Mohan, Disha B., Mukundan, Santhosh, Krishnan, Karthickeyan Chella, Prabhakara, Sushma, Snäll, Johanna, Kearns, Angela, Vandenesch, Francois, Svensson, Mattias, Kotb, Malak, Gopal, Balasubramanian, Arakere, Gayathri, Norrby-Teglund, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980769/ https://www.ncbi.nlm.nih.gov/pubmed/27511873 http://dx.doi.org/10.1038/srep31360 |
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