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Identifying enriched drug fragments as possible candidates for metabolic engineering

BACKGROUND: Fragment-based approaches have now become an important component of the drug discovery process. At the same time, pharmaceutical chemists are more often turning to the natural world and its extremely large and diverse collection of natural compounds to discover new leads that can potenti...

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Detalles Bibliográficos
Autores principales: Sharma, Sunandini, Karri, Kritika, Thapa, Ishwor, Bastola, Dhundy, Ghersi, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980782/
https://www.ncbi.nlm.nih.gov/pubmed/27510651
http://dx.doi.org/10.1186/s12920-016-0205-6