Enantioselective Synthesis of Spirooxindole Enols: Regioselective and Asymmetric [3+2] Cyclization of 3‐Isothiocyanato Oxindoles with Dibenzylidene Ketones

A novel cinchona‐alkaloid‐derived organocatalyst has been developed to catalyze the asymmetric regioselective [3+2] cycloaddition of 3‐isothiocyanato oxindoles with dibenzylidene ketones. A series of spirooxindole enols could be obtained in high yields with good‐to‐excellent diastereo‐ and enantiose...

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Detalles Bibliográficos
Autores principales: Du, Dan, Jiang, Yu, Xu, Qin, Li, Xiao‐Ge, Shi, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981050/
https://www.ncbi.nlm.nih.gov/pubmed/27547639
http://dx.doi.org/10.1002/open.201600034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981050/
https://www.ncbi.nlm.nih.gov/pubmed/27547639
http://dx.doi.org/10.1002/open.201600034

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