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Enantioselective Synthesis of Spirooxindole Enols: Regioselective and Asymmetric [3+2] Cyclization of 3‐Isothiocyanato Oxindoles with Dibenzylidene Ketones

A novel cinchona‐alkaloid‐derived organocatalyst has been developed to catalyze the asymmetric regioselective [3+2] cycloaddition of 3‐isothiocyanato oxindoles with dibenzylidene ketones. A series of spirooxindole enols could be obtained in high yields with good‐to‐excellent diastereo‐ and enantiose...

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Detalles Bibliográficos
Autores principales:	Du, Dan, Jiang, Yu, Xu, Qin, Li, Xiao‐Ge, Shi, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981050/ https://www.ncbi.nlm.nih.gov/pubmed/27547639 http://dx.doi.org/10.1002/open.201600034

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