Melting Point Distribution Analysis of Globally Approved and Discontinued Drugs: A Research for Improving the Chance of Success of Drug Design and Discovery

The melting point (MP), an easily accessible physical parameter, has considerable potential for the judgment of drug‐like properties. However, to the best of our knowledge, there are no useful guidelines for understanding the relationship between the MP and drug‐like properties. To this end, we have...

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Detalles Bibliográficos
Autores principales: Mao, Fei, Kong, Qingya, Ni, Wei, Xu, Xiang, Ling, Dazheng, Lu, Zhengyu, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981057/
https://www.ncbi.nlm.nih.gov/pubmed/27547646
http://dx.doi.org/10.1002/open.201600015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981057/
https://www.ncbi.nlm.nih.gov/pubmed/27547646
http://dx.doi.org/10.1002/open.201600015

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