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Adamantylidene-substituted alkylphosphocholine TCAN26 is more active against Sporothrix schenckii than miltefosine

Sporotrichosis is the most frequent subcutaneous mycosis in the world and its increasing incidence has led to the search for new therapeutic options for its treatment. In this study, we demonstrated that three structural analogues of miltefosine (TCAN26, TC19, and TC70) showed inhibitory activity ag...

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Detalles Bibliográficos
Autores principales: Borba-Santos, Luana Pereira, Ishida, Kelly, Calogeropoulou, Theodora, de Souza, Wanderley, Rozental, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981111/
https://www.ncbi.nlm.nih.gov/pubmed/27581121
http://dx.doi.org/10.1590/0074-02760160088