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Quantification of simvastatin in mice plasma by near-infrared and chemometric analysis of spectral data

Time and cost saving is an essential requirement in pharmacokinetics and bioequivalence studies. The aim of this study is to use a simple, fast, and nondestructive near-infrared transmission spectroscopic method to quantify simvastatin (SMV) concentrations in mice plasma and also to improve SMV bioa...

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Detalles Bibliográficos
Autor principal: Fahmy, Usama A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981156/
https://www.ncbi.nlm.nih.gov/pubmed/27540278
http://dx.doi.org/10.2147/DDDT.S114826