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Quantification of simvastatin in mice plasma by near-infrared and chemometric analysis of spectral data
Time and cost saving is an essential requirement in pharmacokinetics and bioequivalence studies. The aim of this study is to use a simple, fast, and nondestructive near-infrared transmission spectroscopic method to quantify simvastatin (SMV) concentrations in mice plasma and also to improve SMV bioa...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981156/ https://www.ncbi.nlm.nih.gov/pubmed/27540278 http://dx.doi.org/10.2147/DDDT.S114826 |