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A dual brain-targeting curcumin-loaded polymersomes ameliorated cognitive dysfunction in intrahippocampal amyloid-β(1–42)-injected mice

Due to the impermeability of the blood–brain barrier and the nonselective distribution of drugs in the brain, the therapeutic access to intractable neurological disorders is challenging. In this study, dual brain-targeting polymersomes (POs) functionalized by transferrin and Tet-1 peptide (Tf/Tet-1-...

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Detalles Bibliográficos
Autores principales: Jia, Tingting, Sun, Zhiguo, Lu, Ying, Gao, Jie, Zou, Hao, Xie, Fangyuan, Zhang, Guoqing, Xu, Hao, Sun, Duxin, Yu, Yuan, Zhong, Yanqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981163/
https://www.ncbi.nlm.nih.gov/pubmed/27540290
http://dx.doi.org/10.2147/IJN.S94622