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Restriction of Retrotransposon Mobilization in Schizosaccharomyces pombe by Transcriptional Silencing and Higher-Order Chromatin Organization

Uncontrolled propagation of retrotransposons is potentially detrimental to host genome integrity. Therefore, cells have evolved surveillance mechanisms to restrict the mobility of these elements. In Schizosaccharomyces pombe the Tf2 LTR retrotransposons are transcriptionally silenced and are also cl...

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Detalles Bibliográficos
Autores principales: Murton, Heather E., Grady, Patrick J. R., Chan, Tsun Ho, Cam, Hugh P., Whitehall, Simon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981269/
https://www.ncbi.nlm.nih.gov/pubmed/27343236
http://dx.doi.org/10.1534/genetics.116.189118