Saccharomyces cerevisiae TORC1 Controls Histone Acetylation by Signaling Through the Sit4/PP6 Phosphatase to Regulate Sirtuin Deacetylase Nuclear Accumulation

The epigenome responds to changes in the extracellular environment, yet how this information is transmitted to the epigenetic regulatory machinery is unclear. Using a Saccharomyces cerevisiae yeast model, we demonstrate that target of rapamycin complex 1 (TORC1) signaling, which is activated by nitr...

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Detalles Bibliográficos
Autores principales: Workman, Jason J., Chen, Hongfeng, Laribee, R. Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981274/
https://www.ncbi.nlm.nih.gov/pubmed/27343235
http://dx.doi.org/10.1534/genetics.116.188458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981274/
https://www.ncbi.nlm.nih.gov/pubmed/27343235
http://dx.doi.org/10.1534/genetics.116.188458

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