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Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis

Mycobacterium tuberculosis synthesizes intra- and extracellular α-glucans that were believed to originate from separate pathways. The extracellular glucose polymer is the main constituent of the mycobacterial capsule that is thought to be involved in immune evasion and virulence. However, the role o...

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Detalles Bibliográficos
Autores principales: Koliwer-Brandl, Hendrik, Syson, Karl, van de Weerd, Robert, Chandra, Govind, Appelmelk, Ben, Alber, Marina, Ioerger, Thomas R., Jacobs, William R., Geurtsen, Jeroen, Bornemann, Stephen, Kalscheuer, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981310/
https://www.ncbi.nlm.nih.gov/pubmed/27513637
http://dx.doi.org/10.1371/journal.ppat.1005768