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Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis
Mycobacterium tuberculosis synthesizes intra- and extracellular α-glucans that were believed to originate from separate pathways. The extracellular glucose polymer is the main constituent of the mycobacterial capsule that is thought to be involved in immune evasion and virulence. However, the role o...
Autores principales: | Koliwer-Brandl, Hendrik, Syson, Karl, van de Weerd, Robert, Chandra, Govind, Appelmelk, Ben, Alber, Marina, Ioerger, Thomas R., Jacobs, William R., Geurtsen, Jeroen, Bornemann, Stephen, Kalscheuer, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981310/ https://www.ncbi.nlm.nih.gov/pubmed/27513637 http://dx.doi.org/10.1371/journal.ppat.1005768 |
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