Insights into the Conformation of the Membrane Proximal Regions Critical to the Trimerization of the HIV-1 gp41 Ectodomain Bound to Dodecyl Phosphocholine Micelles

The transitioning of the ectodomain of gp41 from a pre-hairpin to a six-helix bundle conformation is a crucial aspect of virus-cell fusion. To gain insight into the intermediary steps of the fusion process we have studied the pH and dodecyl phosphocholine (DPC) micelle dependent trimer association o...

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Detalles Bibliográficos
Autores principales: Louis, John M., Baber, James L., Ghirlando, Rodolfo, Aniana, Annie, Bax, Ad, Roche, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981318/
https://www.ncbi.nlm.nih.gov/pubmed/27513582
http://dx.doi.org/10.1371/journal.pone.0160597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981318/
https://www.ncbi.nlm.nih.gov/pubmed/27513582
http://dx.doi.org/10.1371/journal.pone.0160597

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