Reduction of c-Fos via Overexpression of miR-34a Results in Enhancement of TNF- Production by LPS in Neutrophils from Myelodysplastic Syndrome Patients

Although increased TNF-α has been considered to cause ineffective hematopoiesis in myelodysplastic syndromes (MDS), the mechanisms of TNF-α elevation are not known. We recently found that c-Fos mRNA stabilization under translation-inhibiting stimuli was impaired in MDS-derived neutrophilic granulocy...

Descripción completa

Detalles Bibliográficos
Autores principales: Shikama, Yayoi, Cao, Meiwan, Ono, Tomoyuki, Feng, Xiaomin, Noji, Hideyoshi, Kimura, Hideo, Ogawa, Kazuei, Suzuki, Yuko, Ikeda, Kazuhiko, Takeishi, Yasuchika, Kimura, Junko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981319/
https://www.ncbi.nlm.nih.gov/pubmed/27513856
http://dx.doi.org/10.1371/journal.pone.0158527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981319/
https://www.ncbi.nlm.nih.gov/pubmed/27513856
http://dx.doi.org/10.1371/journal.pone.0158527

Ejemplares similares