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Medial HOXA genes demarcate haematopoietic stem cell fate during human development
Pluripotent stem cells (PSC) may provide a potential source of haematopoietic stem/progenitor cells (HSPCs) for transplantation; however, unknown molecular barriers prevent the self-renewal of PSC-HSPCs. Using two-step differentiation, human embryonic stem cells (hESCs) differentiated in vitro into...
Autores principales: | Dou, Diana R., Calvanese, Vincenzo, Sierra, Maria I., Nguyen, Andrew T., Minasian, Arazin, Saarikoski, Pamela, Sasidharan, Rajkumar, Ramirez, Christina M., Zack, Jerome A., Crooks, Gay M., Galic, Zoran, Mikkola, Hanna K.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981340/ https://www.ncbi.nlm.nih.gov/pubmed/27183470 http://dx.doi.org/10.1038/ncb3354 |
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