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The RNA-Binding Protein, Polypyrimidine Tract-Binding Protein 1 (PTBP1) Is a Key Regulator of CD4 T Cell Activation

We have previously shown that the RNA binding protein, polypyrimidine tract-binding protein (PTBP1) plays a critical role in regulating the expression of CD40L in activated CD4 T cells. This is achieved mechanistically through message stabilization at late times of activation as well as by altered d...

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Detalles Bibliográficos
Autores principales: La Porta, James, Matus-Nicodemos, Rodrigo, Valentín-Acevedo, Aníbal, Covey, Lori R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981342/
https://www.ncbi.nlm.nih.gov/pubmed/27513449
http://dx.doi.org/10.1371/journal.pone.0158708