AMPK Mediates Glucocorticoids Stress-Induced Downregulation of the Glucocorticoid Receptor in Cultured Rat Prefrontal Cortical Astrocytes

Chronic stress induces altered energy metabolism and plays important roles in the etiology of depression, in which the glucocorticoid negative feedback is disrupted due to imbalanced glucocorticoid receptor (GR) functions. The mechanism underlying the dysregulation of GR by chronic stress remains el...

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Detalles Bibliográficos
Autores principales: Yuan, Shi-Ying, Liu, Jue, Zhou, Jun, Lu, Wei, Zhou, Hai-Yun, Long, Li-Hong, Hu, Zhuang-Li, Ni, Lan, Wang, Yi, Chen, Jian-Guo, Wang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981361/
https://www.ncbi.nlm.nih.gov/pubmed/27513844
http://dx.doi.org/10.1371/journal.pone.0159513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981361/
https://www.ncbi.nlm.nih.gov/pubmed/27513844
http://dx.doi.org/10.1371/journal.pone.0159513

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