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Angiogenic Factor AGGF1 Activates Autophagy with an Essential Role in Therapeutic Angiogenesis for Heart Disease

AGGF1 is an angiogenic factor with therapeutic potential to treat coronary artery disease (CAD) and myocardial infarction (MI). However, the underlying mechanism for AGGF1-mediated therapeutic angiogenesis is unknown. Here, we show for the first time that AGGF1 activates autophagy, a housekeeping ca...

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Detalles Bibliográficos
Autores principales: Lu, Qiulun, Yao, Yufeng, Hu, Zhenkun, Hu, Changqing, Song, Qixue, Ye, Jian, Xu, Chengqi, Wang, Annabel Z., Chen, Qiuyun, Wang, Qing Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981375/
https://www.ncbi.nlm.nih.gov/pubmed/27513923
http://dx.doi.org/10.1371/journal.pbio.1002529