Association of FMO3 Variants and Trimethylamine N-Oxide Concentration, Disease Progression, and Mortality in CKD Patients

Elevated levels of circulating pro-atherogenic uremic solutes, particularly trimethylamine N-oxide (TMAO), have been implicated in cardiovascular disease development in patients with chronic kidney disease (CKD). TMAO is generated from trimethylamine (TMA) via metabolism by hepatic flavin-containing...

Descripción completa

Detalles Bibliográficos
Autores principales: Robinson-Cohen, Cassianne, Newitt, Richard, Shen, Danny D., Rettie, Allan E., Kestenbaum, Bryan R., Himmelfarb, Jonathan, Yeung, Catherine K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981377/
https://www.ncbi.nlm.nih.gov/pubmed/27513517
http://dx.doi.org/10.1371/journal.pone.0161074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981377/
https://www.ncbi.nlm.nih.gov/pubmed/27513517
http://dx.doi.org/10.1371/journal.pone.0161074

Ejemplares similares