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Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart

Platelet-derived growth factors (PDGFs) are key regulators of mesenchymal cells in vertebrate development. To what extent PDGFs also exert beneficial homeostatic or reparative roles in adult organs, as opposed to adverse fibrogenic responses in pathology, are unclear. PDGF signaling plays critical r...

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Detalles Bibliográficos
Autores principales: Gallini, Radiosa, Huusko, Jenni, Ylä-Herttuala, Seppo, Betsholtz, Christer, Andrae, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981378/
https://www.ncbi.nlm.nih.gov/pubmed/27513343
http://dx.doi.org/10.1371/journal.pone.0160930