Re-Cloning the N27 Dopamine Cell Line to Improve a Cell Culture Model of Parkinson's Disease

Parkinson’s disease is characterized by the death of dopaminergic neurons in the substantia nigra. To understand the molecular mechanisms of the disease, an in vitro model is important. In the 1990s, we used the SV40 large T antigen to immortalize dopaminergic neurons derived from Embryonic Day 14 r...

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Detalles Bibliográficos
Autores principales: Gao, Lu, Zhou, Wenbo, Symmes, Breanna, Freed, Curt R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981411/
https://www.ncbi.nlm.nih.gov/pubmed/27512998
http://dx.doi.org/10.1371/journal.pone.0160847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981411/
https://www.ncbi.nlm.nih.gov/pubmed/27512998
http://dx.doi.org/10.1371/journal.pone.0160847

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