Linagliptin Ameliorates Methylglyoxal-Induced Peritoneal Fibrosis in Mice

Recent studies have reported increases of methylglyoxal (MGO) in peritoneal dialysis patients, and that MGO-mediated inflammation plays an important role in the development of peritoneal fibrosis through production of transforming growth factor-β1 (TGF-β1). Linagliptin, a dipeptidyl peptidase-4 inhi...

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Detalles Bibliográficos
Autores principales: Nagai, Takuo, Doi, Shigehiro, Nakashima, Ayumu, Irifuku, Taisuke, Sasaki, Kensuke, Ueno, Toshinori, Masaki, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981421/
https://www.ncbi.nlm.nih.gov/pubmed/27513960
http://dx.doi.org/10.1371/journal.pone.0160993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981421/
https://www.ncbi.nlm.nih.gov/pubmed/27513960
http://dx.doi.org/10.1371/journal.pone.0160993

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