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Linagliptin Ameliorates Methylglyoxal-Induced Peritoneal Fibrosis in Mice
Recent studies have reported increases of methylglyoxal (MGO) in peritoneal dialysis patients, and that MGO-mediated inflammation plays an important role in the development of peritoneal fibrosis through production of transforming growth factor-β1 (TGF-β1). Linagliptin, a dipeptidyl peptidase-4 inhi...
Autores principales: | Nagai, Takuo, Doi, Shigehiro, Nakashima, Ayumu, Irifuku, Taisuke, Sasaki, Kensuke, Ueno, Toshinori, Masaki, Takao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981421/ https://www.ncbi.nlm.nih.gov/pubmed/27513960 http://dx.doi.org/10.1371/journal.pone.0160993 |
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