Ethanol and Acetaminophen Synergistically Induce Hepatic Aggregation and TCH346-Insensitive Nuclear Translocation of GAPDH

The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) signals during cellular stress via several post-translational modifications that change its folding properties, protein-protein interactions and sub-cellular localization. We examined GAPDH properties in acute mouse liver injury...

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Detalles Bibliográficos
Autores principales: Snider, Natasha T., Portney, Daniel A., Willcockson, Helen H., Maitra, Dhiman, Martin, Hope C., Greenson, Joel K., Omary, M. Bishr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981434/
https://www.ncbi.nlm.nih.gov/pubmed/27513663
http://dx.doi.org/10.1371/journal.pone.0160982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981434/
https://www.ncbi.nlm.nih.gov/pubmed/27513663
http://dx.doi.org/10.1371/journal.pone.0160982

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