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Ethanol and Acetaminophen Synergistically Induce Hepatic Aggregation and TCH346-Insensitive Nuclear Translocation of GAPDH
The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) signals during cellular stress via several post-translational modifications that change its folding properties, protein-protein interactions and sub-cellular localization. We examined GAPDH properties in acute mouse liver injury...
Autores principales: | Snider, Natasha T., Portney, Daniel A., Willcockson, Helen H., Maitra, Dhiman, Martin, Hope C., Greenson, Joel K., Omary, M. Bishr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981434/ https://www.ncbi.nlm.nih.gov/pubmed/27513663 http://dx.doi.org/10.1371/journal.pone.0160982 |
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