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DHA but Not EPA Emulsions Preserve Neurological and Mitochondrial Function after Brain Hypoxia-Ischemia in Neonatal Mice

BACKGROUND AND PURPOSE: Treatment with triglyceride emulsions of docosahexaenoic acid (tri-DHA) protected neonatal mice against hypoxia-ischemia (HI) brain injury. The mechanism of this neuroprotection remains unclear. We hypothesized that administration of tri-DHA enriches HI-brains with DHA/DHA me...

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Detalles Bibliográficos
Autores principales: Mayurasakorn, Korapat, Niatsetskaya, Zoya V., Sosunov, Sergey A., Williams, Jill J., Zirpoli, Hylde, Vlasakov, Iliyan, Deckelbaum, Richard J., Ten, Vadim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981459/
https://www.ncbi.nlm.nih.gov/pubmed/27513579
http://dx.doi.org/10.1371/journal.pone.0160870