Candidate mechanisms underlying the association between sleep-wake disruptions and Alzheimer’s disease

During wakefulness, extracellular levels of metabolites in the brain increase. These include amyloid beta (Aβ), which contributes to the pathogenesis of Alzheimer’s disease (AD). Counterbalancing their accumulation in the brain, sleep facilitates the removal of these metabolites from the extracellul...

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Detalles Bibliográficos
Autores principales: Cedernaes, Jonathan, Osorio, Ricardo S., Varga, Andrew W., Kam, Korey, Schioöth, Helgi B., Benedict, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981560/
https://www.ncbi.nlm.nih.gov/pubmed/26996255
http://dx.doi.org/10.1016/j.smrv.2016.02.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981560/
https://www.ncbi.nlm.nih.gov/pubmed/26996255
http://dx.doi.org/10.1016/j.smrv.2016.02.002

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