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Monitoring antigenic protein integrity during glycoconjugate vaccine synthesis using capillary electrophoresis-mass spectrometry

A capillary electrophoresis-mass spectrometry (CE-MS) method was developed for the characterization and integrity assessment of the Mycobacterium tuberculosis (MTB) antigens TB10.4 and Ag85B and their chemically produced glycoconjugates, which are glycovaccine candidates against tuberculosis (TB). I...

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Detalles Bibliográficos
Autores principales: Tengattini, Sara, Domínguez-Vega, Elena, Temporini, Caterina, Terreni, Marco, Somsen, Govert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981626/
https://www.ncbi.nlm.nih.gov/pubmed/27372716
http://dx.doi.org/10.1007/s00216-016-9723-5