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Monitoring antigenic protein integrity during glycoconjugate vaccine synthesis using capillary electrophoresis-mass spectrometry
A capillary electrophoresis-mass spectrometry (CE-MS) method was developed for the characterization and integrity assessment of the Mycobacterium tuberculosis (MTB) antigens TB10.4 and Ag85B and their chemically produced glycoconjugates, which are glycovaccine candidates against tuberculosis (TB). I...
Autores principales: | Tengattini, Sara, Domínguez-Vega, Elena, Temporini, Caterina, Terreni, Marco, Somsen, Govert W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981626/ https://www.ncbi.nlm.nih.gov/pubmed/27372716 http://dx.doi.org/10.1007/s00216-016-9723-5 |
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