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In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis

Toxoplasma gondii is an obligate intracellular parasite that invades host cells and replicates within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite secretes an array of dense granule proteins (GRAs) into the nascent parasitophorous vacuole. These GRAs are belie...

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Detalles Bibliográficos
Autores principales: Nadipuram, Santhosh M., Kim, Elliot W., Vashisht, Ajay A., Lin, Andrew H., Bell, Hannah N., Coppens, Isabelle, Wohlschlegel, James A., Bradley, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981711/
https://www.ncbi.nlm.nih.gov/pubmed/27486190
http://dx.doi.org/10.1128/mBio.00808-16