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In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis
Toxoplasma gondii is an obligate intracellular parasite that invades host cells and replicates within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite secretes an array of dense granule proteins (GRAs) into the nascent parasitophorous vacuole. These GRAs are belie...
Autores principales: | Nadipuram, Santhosh M., Kim, Elliot W., Vashisht, Ajay A., Lin, Andrew H., Bell, Hannah N., Coppens, Isabelle, Wohlschlegel, James A., Bradley, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981711/ https://www.ncbi.nlm.nih.gov/pubmed/27486190 http://dx.doi.org/10.1128/mBio.00808-16 |
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