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The Cell Wall Polymer Lipoteichoic Acid Becomes Nonessential in Staphylococcus aureus Cells Lacking the ClpX Chaperone

Lipoteichoic acid (LTA) is an important cell wall component of Gram-positive bacteria and a promising target for the development of vaccines and antimicrobial compounds against Staphylococcus aureus. Here we demonstrate that mutations in the conditionally essential ltaS (LTA synthase) gene arise spo...

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Detalles Bibliográficos
Autores principales: Bæk, Kristoffer T., Bowman, Lisa, Millership, Charlotte, Dupont Søgaard, Mia, Kaever, Volkhard, Siljamäki, Pia, Savijoki, Kirsi, Varmanen, Pekka, Nyman, Tuula A., Gründling, Angelika, Frees, Dorte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981727/
https://www.ncbi.nlm.nih.gov/pubmed/27507828
http://dx.doi.org/10.1128/mBio.01228-16