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Evaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid

PURPOSE: Cancer spread to the central nervous system (CNS) often is diagnosed late and is unresponsive to therapy. Mechanisms of tumor dissemination and evolution within the CNS are largely unknown because of limited access to tumor tissue. MATERIALS AND METHODS: We sequenced 341 cancer-associated g...

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Detalles Bibliográficos
Autores principales: Pentsova, Elena I., Shah, Ronak H., Tang, Jiabin, Boire, Adrienne, You, Daoqi, Briggs, Samuel, Omuro, Antonio, Lin, Xuling, Fleisher, Martin, Grommes, Christian, Panageas, Katherine S., Meng, Fanli, Selcuklu, S. Duygu, Ogilvie, Shahiba, Distefano, Natalie, Shagabayeva, Larisa, Rosenblum, Marc, DeAngelis, Lisa M., Viale, Agnes, Mellinghoff, Ingo K., Berger, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981784/
https://www.ncbi.nlm.nih.gov/pubmed/27161972
http://dx.doi.org/10.1200/JCO.2016.66.6487