Elimination of microglia improves cognitive function following cranial irradiation

Cranial irradiation for the treatment of brain cancer elicits progressive and severe cognitive dysfunction that is associated with significant neuropathology. Radiation injury in the CNS has been linked to persistent microglial activation, and we find upregulation of pro-inflammatory genes even 6 we...

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Detalles Bibliográficos
Autores principales: Acharya, Munjal M., Green, Kim N., Allen, Barrett D., Najafi, Allison R., Syage, Amber, Minasyan, Harutyun, Le, Mi T., Kawashita, Takumi, Giedzinski, Erich, Parihar, Vipan K., West, Brian L., Baulch, Janet E., Limoli, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981848/
https://www.ncbi.nlm.nih.gov/pubmed/27516055
http://dx.doi.org/10.1038/srep31545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981848/
https://www.ncbi.nlm.nih.gov/pubmed/27516055
http://dx.doi.org/10.1038/srep31545

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