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Elimination of microglia improves cognitive function following cranial irradiation
Cranial irradiation for the treatment of brain cancer elicits progressive and severe cognitive dysfunction that is associated with significant neuropathology. Radiation injury in the CNS has been linked to persistent microglial activation, and we find upregulation of pro-inflammatory genes even 6 we...
Autores principales: | Acharya, Munjal M., Green, Kim N., Allen, Barrett D., Najafi, Allison R., Syage, Amber, Minasyan, Harutyun, Le, Mi T., Kawashita, Takumi, Giedzinski, Erich, Parihar, Vipan K., West, Brian L., Baulch, Janet E., Limoli, Charles L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981848/ https://www.ncbi.nlm.nih.gov/pubmed/27516055 http://dx.doi.org/10.1038/srep31545 |
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