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The nephronophthisis-related gene ift-139 is required for ciliogenesis in Caenorhabditis elegans

Defects in cilia cause a spectrum of diseases known as ciliopathies. Nephronophthisis, a ciliopathy, is the most common genetic cause of renal disease. Here, I cloned and analysed a nephronophthisis-related gene ift-139 in Caenorhabditis elegans. ift-139 was exclusively expressed in ciliated neurons...

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Detalles Bibliográficos
Autor principal: Niwa, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981862/
https://www.ncbi.nlm.nih.gov/pubmed/27515926
http://dx.doi.org/10.1038/srep31544