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The opposite prognostic effect of NDUFS1 and NDUFS8 in lung cancer reflects the oncojanus role of mitochondrial complex I

A recent surge of research on complex I mitochondrial DNA indicates that complex I disassembly regulated by mutation threshold plays a critical role in tumor progression. However, nuclear DNA (nDNA)-encoded core subunits are still a neglected area for cancer investigation. In this study, respective...

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Detalles Bibliográficos
Autores principales: Su, Chia-Yi, Chang, Yu-Chan, Yang, Chih-Jen, Huang, Ming-Shyan, Hsiao, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981865/
https://www.ncbi.nlm.nih.gov/pubmed/27516145
http://dx.doi.org/10.1038/srep31357