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Optimized Standard Operating Procedures for the Analysis of Cerebrospinal Fluid Aβ(42) and the Ratios of Aβ Isoforms Using Low Protein Binding Tubes

Background: Reduced cerebrospinal fluid (CSF) concentration of amyloid-β(1-42) (Aβ(1-42)) reflects the presence of amyloidopathy in brains of subjects with Alzheimer’s disease (AD). Objective: To qualify the use of Aβ(1-42)/Aβ(1-40) for improvement of standard operating procedures (SOP) for measurem...

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Detalles Bibliográficos
Autores principales: Vanderstichele, Hugo Marcel Johan, Janelidze, Shorena, Demeyer, Leentje, Coart, Els, Stoops, Erik, Herbst, Victor, Mauroo, Kimberley, Brix, Britta, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981898/
https://www.ncbi.nlm.nih.gov/pubmed/27258423
http://dx.doi.org/10.3233/JAD-160286