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Human umbilical cord-derived mesenchymal stem cells protect against experimental colitis via CD5(+) B regulatory cells
BACKGROUND: To clarify the effect of human umbilical cord-derived mesenchymal stem cell (hUC-MSCs) treatment on colitis and to explore the role of CD5(+) B cells in MSC therapy. METHODS: The trinitrobenzenesulfonic acid (TNBS)-induced colitis mouse model was used. HUC-MSCs were transferred peritonea...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981968/ https://www.ncbi.nlm.nih.gov/pubmed/27515534 http://dx.doi.org/10.1186/s13287-016-0376-2 |