Determining the mode of action of anti-mycobacterial C17 diyne natural products using expression profiling: evidence for fatty acid biosynthesis inhibition

BACKGROUND: The treatment of microbial infections is becoming increasingly challenging because of limited therapeutic options and the growing number of pathogenic strains that are resistant to current antibiotics. There is an urgent need to identify molecules with novel modes of action to facilitate...

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Detalles Bibliográficos
Autores principales: Li, Haoxin, Cowie, Andrew, Johnson, John A., Webster, Duncan, Martyniuk, Christopher J., Gray, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981992/
https://www.ncbi.nlm.nih.gov/pubmed/27514659
http://dx.doi.org/10.1186/s12864-016-2949-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981992/
https://www.ncbi.nlm.nih.gov/pubmed/27514659
http://dx.doi.org/10.1186/s12864-016-2949-y

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