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Transient receptor potential ankyrin 1 (TRPA1) is functionally expressed in primary human osteoarthritic chondrocytes

BACKGROUND: Transient receptor potential ankyrin 1 (TRPA1) is a membrane-associated cation channel, widely expressed in neuronal cells and involved in nociception and neurogenic inflammation. We showed recently that TRPA1 mediates cartilage degradation and joint pain in the MIA-model of osteoarthrit...

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Detalles Bibliográficos
Autores principales: Nummenmaa, Elina, Hämäläinen, Mari, Moilanen, Lauri J., Paukkeri, Erja-Leena, Nieminen, Riina M., Moilanen, Teemu, Vuolteenaho, Katriina, Moilanen, Eeva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982008/
https://www.ncbi.nlm.nih.gov/pubmed/27515912
http://dx.doi.org/10.1186/s13075-016-1080-4