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JNK/SAPK Signaling Is Essential for Efficient Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells

Reprogramming of somatic cells to the phenotypic state termed “induced pluripotency” is thought to occur through three consecutive stages: initiation, maturation, and stabilisation. The initiation phase is stochastic but nevertheless very important as it sets the gene expression pattern that permits...

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Detalles Bibliográficos
Autores principales: Neganova, Irina, Shmeleva, Evgenija, Munkley, Jennifer, Chichagova, Valeria, Anyfantis, George, Anderson, Rhys, Passos, Joao, Elliott, David J., Armstrong, Lyle, Lako, Majlinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982072/
https://www.ncbi.nlm.nih.gov/pubmed/26867034
http://dx.doi.org/10.1002/stem.2327