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lin28 proteins promote expression of 17∼92 family miRNAs during amphibian development

Background: Lin28 proteins are post‐transcriptional regulators of gene expression with multiple roles in development and the regulation of pluripotency in stem cells. Much attention has focussed on Lin28 proteins as negative regulators of let‐7 miRNA biogenesis; a function that is conserved in sever...

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Detalles Bibliográficos
Autores principales: Warrander, Fiona, Faas, Laura, Kovalevskiy, Oleg, Peters, Daniel, Coles, Mark, Antson, Alfred A., Genever, Paul, Isaacs, Harry V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982076/
https://www.ncbi.nlm.nih.gov/pubmed/26447465
http://dx.doi.org/10.1002/dvdy.24358