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Control of the thymic medulla and its influence on αβT‐cell development

The thymus is a primary lymphoid tissue that supports the generation of αβT cells. In this review, we describe the processes that give rise to the thymus medulla, a site that nurtures self‐tolerant T‐cell generation following positive selection events that take place in the cortex. To summarize the...

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Detalles Bibliográficos
Autores principales: Lucas, Beth, McCarthy, Nicholas I., Baik, Song, Cosway, Emilie, James, Kieran D., Parnell, Sonia M., White, Andrea J., Jenkinson, William E., Anderson, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982089/
https://www.ncbi.nlm.nih.gov/pubmed/27088905
http://dx.doi.org/10.1111/imr.12406