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Specific inhibition of c-Jun N-terminal kinase delays preterm labour and reduces mortality

Preterm labour (PTL) is commonly associated with infection and/or inflammation. Lipopolysaccharide (LPS) from different bacteria can be used to independently or mutually activate Jun N-terminal kinase (JNK)/AP1- or NF-κB-driven inflammatory pathways that lead to PTL. Previous studies using Salmonell...

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Detalles Bibliográficos
Autores principales: Pirianov, Grisha, MacIntyre, David A, Lee, Yun, Waddington, Simon N, Terzidou, Vasso, Mehmet, Huseyin, Bennett, Phillip R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982111/
https://www.ncbi.nlm.nih.gov/pubmed/26183892
http://dx.doi.org/10.1530/REP-15-0258