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DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression
BACKGROUND: The Synapsins (SYN1, SYN2, and SYN3) are important players in the adult brain, given their involvement in synaptic transmission and plasticity, as well as in the developing brain through roles in axon outgrowth and synaptogenesis. We and others previously reported gene expression dysregu...
Autores principales: | Cruceanu, Cristiana, Kutsarova, Elena, Chen, Elizabeth S., Checknita, David R., Nagy, Corina, Lopez, Juan Pablo, Alda, Martin, Rouleau, Guy A., Turecki, Gustavo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982122/ https://www.ncbi.nlm.nih.gov/pubmed/27515700 http://dx.doi.org/10.1186/s12888-016-0989-0 |
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